yxeQ
168
cis-aconitate decarboxylase
locus
BSU_39460
Molecular weight
47.64 kDa
pI
5.94
function
metabolite conversion
product
cis-aconitate decarboxylase
essential
no
synonyms
yxeQ
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG2079 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
4,055,536 4,056,873
Advertisement
The protein
Catalyzed reaction/ biological activity
cis-aconitate --> itaconate + CO2 [pubmed|32647315]
Protein family
prpD family (with [protein|602EAB591A550F68C14F35F6E5F0A91C3B997343|mmgE], according to UniProt)
Structure
[PDB|7BRA] [pubmed|32647315]
[AF|P54956]
Expression and Regulation
Operons
genes
[gene|19E6EF9CCA31440EAC046F8D6CA98B6A08589D58|yxeK]-[gene|EBC2B9107AD50DD8F8174FC0BE4AD90DEE6A7CCA|snaB]-[gene|D96EEDABB73AC66E6AB772431819E7C767DC8B9A|yxeM]-[gene|FFD5F07480A0E5A74852C69C436EE289BA72FC7F|yxeN]-[gene|F8C800CF71D21A1F3265977C4F0EE191D0FFE36A|yxeO]-[gene|C99AA3FDBB561BCED60915078DC746690C071753|sndB]-[gene|7DDB283173267AA106DC277787AAAB4F4F9975F4|yxeQ]
description
[Pubmed|10746760]
regulation
repressed in the presence of cysteine ([protein|50930C56C27D22715620A350220E3C56ADB41020|cymR]) [Pubmed|16513748]
regulatory mechanism
[protein|50930C56C27D22715620A350220E3C56ADB41020|cymR]: repression, [Pubmed|16513748], in [regulon|protein:50930C56C27D22715620A350220E3C56ADB41020|cymR regulon]
sigma factors
[protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA]: sigma factor, [Pubmed|16513748], in [regulon|protein:360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA regulon]
additional information
the amount of the mRNA is substantially decreased upon depletion of [gene|872CCB5A49C9000BD95E4B0472556D5F60F7D7A4|RNase Y] [PubMed|21815947]
Biological materials
Mutant
MGNA-B713 (yxeQ::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1712 NBRP B. subtilis, Japan]
BKE39460 ([gene|7DDB283173267AA106DC277787AAAB4F4F9975F4|yxeQ]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE39460 BGSC], [Pubmed|28189581], upstream reverse: _UP1_ACCTGCTGTCAGCCCTTGTT, downstream forward: _UP4_TAAGATCAACTCTATTCGGT
BKK39460 ([gene|7DDB283173267AA106DC277787AAAB4F4F9975F4|yxeQ]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK39460 BGSC], [Pubmed|28189581], upstream reverse: _UP1_ACCTGCTGTCAGCCCTTGTT, downstream forward: _UP4_TAAGATCAACTCTATTCGGT
References
Page visits: 2471
Time of last update: 2024-11-08 13:26:11
Author of last update: Jstuelk