aseR

aseR
168

transcriptional repressor of the ArsR family, of aseA and aseR

Locus
BSU_05330
Molecular weight
12.95 kDa
Isoelectric point
6.31
Protein length
111 aaSequenceBlast
Gene length
336 bpSequenceBlast
Function
regulation of As (III) efflux
Product
transcriptional repressor (ArsR family)
Essential
no
Synonyms
aseR, ydeT
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG0640 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
579,541 → 579,876
The protein
Protein family
ArsR family
Domains
HTH arsR-type domain (aa 1-105) (according to UniProt)
Structure
2OQG (PDB) (from Rhodococcus sp., 27% identity)
P96677 (AlphaFold)
Effectors of protein activity
As(III) acts as molecular inducer PubMed
Expression and Regulation
Operons
Genes
aseR-aseA-ydzS/1-ydzS/2
Description
PubMed
Regulation
induced by As(III) (AseR) PubMed
Regulatory mechanism
AseR: repression, PubMed, in aseR regulon
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aseR->ydzS/2

2025-03-13 21:29:27

Bzhu

68

ebd49d23227107bcbdefbcbe0a6817686ade5fec

0794044A4BC2C55CDC69519799521B48FFBA83EE

Biological materials
Mutant
MGNA-C168 (ydeT::erm), available at the NBRP B. subtilis, Japan
BKE05330 (ΔaseR::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATATGAGCTCCTCCTTCCC,  downstream forward: _UP4_TGTTGCCAGTAAGGAGGCAT
BKK05330 (ΔaseR::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATATGAGCTCCTCCTTCCC,  downstream forward: _UP4_TGTTGCCAGTAAGGAGGCAT
References
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Time of last update: 2025-04-06 07:03:28

Author of last update: Melvin.boenninger