comGF

comGF
168

DNA transport machinery

Locus
BSU_24680
Molecular weight
14.14 kDa
Isoelectric point
5.55
Protein length
127 aaSequenceBlast
Gene length
384 bpSequenceBlast
Function
genetic competence, DNA uptake
Product
DNA transport machinery
Essential
no
Synonyms
comGF
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG4940 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
2,556,512 → 2,556,895
The protein
Structure
P25958 (AlphaFold)
Localization
integral membrane protein PubMed
Expression and Regulation
Operons
Genes
comGA-comGB-comGC-comGD-comGE-comGF-comGG-spoIIIL
Description
PubMed
Regulation
expressed early during sporulation in the forespore (SigF) PubMed
Regulatory mechanism
ComK: activation, PubMed, in comK regulon
Sigma factors
SigA: sigma factor, PubMed, in sigA regulon
SigF: sigma factor, PubMed, in sigF regulon
Additional information
the ''comGA-comGB-comGC-comGD-comGE-comGF-comGG-spoIIIL'' operon requires NusA for expression Reference
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comGA→spoIIIL

2025-03-26 08:15:56

ghost

99

68b5c7c810efc0f97977f58e74fdbac224ab84c2

180BC451CD3457041F2E10E00872F9C6ECB091B7

Biological materials
Mutant
BKE24680 (ΔcomGF::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CAAAAAGACTGAGAGCGAAA,  downstream forward: _UP4_TGAATGTATCGTACAAGAGG
BKK24680 (ΔcomGF::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CAAAAAGACTGAGAGCGAAA,  downstream forward: _UP4_TGAATGTATCGTACAAGAGG
BP914 (Δ(comGA-comGB-comGC-comGD-comGE-comGF-comGG)::phleo), available in Fabian Commichau's lab
References
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DD266DC0D78B5C5E82EED7CC7F55D0CF8FB4BF7A

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Time of last update: 2025-04-05 20:22:15

Author of last update: Jstuelk