flhP

flhP
168

flagellar hook-basal body rod protein, required for hook assembly

Locus
BSU_36390
Molecular weight
29.25 kDa
Isoelectric point
4.59
Protein length
269 aaSequenceBlast
Gene length
810 bpSequenceBlast
Function
motility and chemotaxis
Product
flagellar hook-basal body rod protein
Essential
no
Synonyms
flhP, yvyB
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG4786 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
3,745,436  3,746,245
Phenotypes of a mutant
lack of SigD-dependent gene expression (no ''hag'' expression), no motility  PubMed
defective in Swarming and flagellar assembly PubMed
The protein
Catalyzed reaction/ biological activity
assembly of the flagellar hook PubMed
part of the flagellar rod-hook (in FliE-FlgB-FlgC-FlhO-FlhP-FlgE out, connection to Hag) PubMed
Protein family
Flagella basal body rod proteins family (according to UniProt)
Structure
5WRH (PDB) (from Salmonella typhimurium, 31% identity) PubMed
P39753 (AlphaFold)
Paralogous protein(s)
FlhO, FlgE
Localization
extracellular (no signal peptide) PubMed
flagellum hook (according to UniProt)
Expression and Regulation
Operons
Genes
flhO-flhP
Description
PubMed
Sigma factors
SigD: sigma factor, PubMed, in sigD regulon
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flhO→flhP

2025-03-16 05:12:24

ghost

95

385b168442c3303a06fdd6bd502f1aa8ac4ee20f

E7BD43BA202568F81E22897F4FC7365908069813

Biological materials
Mutant
BKE36390 (flhP::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATAGTTGATGTCCCCCGTT,  downstream forward: _UP4_TAATAAGAAAATGGGCGTTT
BKK36390 (flhP::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATAGTTGATGTCCCCCGTT,  downstream forward: _UP4_TAATAAGAAAATGGGCGTTT
References
Reviews
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Original Publications
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13F35BC7EE8215D7A92A639BEB18647AC276D215

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Time of last update: 2025-04-04 22:37:55

Author of last update: Jstuelk