gdh

gdh
168

glucose 1-dehydrogenase (NAD)

Locus
BSU_03930
Molecular weight
27.94 kDa
Isoelectric point
5.08
Protein length
261 aaSequenceBlast
Gene length
786 bpSequenceBlast
Function
germination
Product
glucose 1-dehydrogenase (NAD)
Essential
no
E.C.
1.1.1.47
Synonyms
gdh
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG1028 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
445,344 → 446,129
The protein
Catalyzed reaction/ biological activity
Beta-D-glucose + NAD(P)+ --> D-glucono-1,5-lactone + NAD(P)H (according to UniProt)
Beta-D-glucose + NAD+ --> D-glucono-1,5-lactone + NADH (according to UniProt)
Protein family
Short-chain dehydrogenases/reductases (SDR) family (according to UniProt)
Structure
3AUS (PDB) (from B. megaterium, 83% identity) PubMed
P12310 (AlphaFold)
Paralogous protein(s)
YhdF, YdcF
YdaD, (35,8%)
YkvO, (34,8%)
YhxC, (34,1%)
YhxD, (33,5%)
YcdF, (53%)
Expression and Regulation
Operons
Genes
glcU-gdh
Description
PubMed
Regulation
expressed during sporulation (SigG, SpoVT) PubMed
Regulatory mechanism
SpoVT: repression, PubMed, in spoVT regulon
Sigma factors
SigG: sigma factor, PubMed, in sigG regulon
Open in new tab

glcU→gdh

2025-03-17 17:33:35

ghost

120

16e0c9c3bee64d8f63243f9c4e2bb309da425435

684036B04938AABA3E506CAD88A18F69D2A51153

Biological materials
Mutant
BKE03930 (Δgdh::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_ATACATATACATCCTCCTCC,  downstream forward: _UP4_TAAACATAAAAAGCGACCCA
BKK03930 (Δgdh::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_ATACATATACATCCTCCTCC,  downstream forward: _UP4_TAAACATAAAAAGCGACCCA
References
Loading

CA4597C6253CCF7D7954686A30AF041808BDF8E5

Page visits: 5222

Time of last update: 2025-04-07 00:11:01

Author of last update: Jstuelk