mdtR

mdtR
168

transcription repressor of the multidrug-resistance mdtR-mdtP operon

Locus
BSU_32870
Molecular weight
17.26 kDa
Isoelectric point
6.38
Protein length
155 aaSequenceBlast
Gene length
468 bpSequenceBlast
Function
regulation of the multidrug-resistance mdtR-mdtP operon
Product
transcription repressor (MarR family)
Essential
no
Synonyms
mdtR, yusO
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG1846 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
3,374,492  3,374,959
The protein
Protein family
MarR family
Domains
HTH marR-type domain (aa 4-140) (according to UniProt)
Structure
1S3J (PDB)
O32181 (AlphaFold)
Expression and Regulation
Operons
Genes
mdtR-mdtP
Description
PubMed
Regulatory mechanism
MdtR: repression, PubMed, in mdtR regulon
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mdtR→mdtP

2025-04-02 10:06:59

ghost

114

e8ef0633959f1f2e66057727f720be97f7312a4d

F311909F49C8D0FC01C8D2C80963778BC55777F7

Biological materials
Mutant
MGNA-B595 (yusO::erm), available at the NBRP B. subtilis, Japan
GP1115 (spc), available in Jörg Stülke's lab
BKE32870 (mdtR::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATATTCATTTCCCCTCTGT,  downstream forward: _UP4_CAAAACATGAAAAGAGGAAA
BKK32870 (mdtR::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATATTCATTTCCCCTCTGT,  downstream forward: _UP4_CAAAACATGAAAAGAGGAAA
References
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Page visits: 3153

Time of last update: 2025-04-06 15:38:43

Author of last update: Melvin.boenninger