ndh

ndh
168

NADH dehydrogenase (Menaquinone 7 & no proton)

Locus
BSU_12290
Molecular weight
41.79 kDa
Isoelectric point
6.29
Protein length
392 aaSequenceBlast
Gene length
1179 bpSequenceBlast
Function
respiration
Product
NADH dehydrogenase (Menaquinone 7 & no proton)
Essential
no
Synonyms
ndh, yjlD
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG1252 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
1,299,074 1,300,252
Phenotypes of a mutant
inactivation of ndh facilitates growth without a cell wall (due to reduction of oxidative stress) PubMed
poor growth PubMed
non-transformable PubMed
The protein
Protein family
NADH dehydrogenase family (with YutJ and YumB, according to UniProt)
Cofactors
FAD PubMed
Structure
4NWZ (PDB) (from C. thermarum, 42% identity) PubMed
P80861 (AlphaFold)
Paralogous protein(s)
YumB
Localization
membrane associated PubMed
Additional information
belongs to the 100 most abundant proteins PubMed
Expression and Regulation
Operons
Genes
yjlC-ndh
Description
PubMed
Regulation
induced at high NADH+ levels (Rex) PubMed
repressed under anaerobic conditions (ResD) PubMed
Regulatory mechanism
Rex: repression, PubMed, in rex regulon
stringent response: negative regulation, in stringent response
ResD: repression, PubMed, in resD regulon
Open in new tab

yjlC→ndh

2025-03-28 06:46:30

Jstuelk

160

8fc075b2517874a07db87d69d9d785f0de7f3d21

1C60502BB7D833D4CC4509CD6E259B0F8D511F21

Genes
yjlB-yjlC-ndh
Description
PubMed
Open in new tab

yjlB→ndh

2025-03-31 23:41:58

Jstuelk

140

d86a69dcbb03e87c0c11960d4290b254a76a2100

D56200C8EE048511C4EFA1B76D998771F9C5F8C9

Biological materials
Mutant
MGNA-A358 (yjlD::erm), available at the NBRP B. subtilis, Japan
BKE12290 (ndh::erm trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CATCGTATATCCTCCGTCCT, downstream forward: _UP4_TAATCCTTTTAATGAATCTG
BKK12290 (ndh::kan trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CATCGTATATCCTCCGTCCT, downstream forward: _UP4_TAATCCTTTTAATGAATCTG
References
Loading

56F407D408272F3674612C9CDFE4A922680EC694

Page visits: 7797

Time of last update: 2025-04-06 22:18:41

Author of last update: Jstuelk