sbcE

sbcE
168

SMC-like protein, involved in DNA double-strand break repair and competence

Locus
BSU_09920
Molecular weight
110.96 kDa
Isoelectric point
5.79
Protein length
963 aaSequenceBlast
Gene length
2892 bpSequenceBlast
Function
DNA double-strand break repair and competence
Product
SMC-like protein
Essential
no
Synonyms
sbcE, yhaN
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG4717 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
1,066,077  1,068,968
Phenotypes of a mutant
sensitive to DNA damage PubMed
The protein
Structure
O08455 (AlphaFold)
Localization
Membrane-proximal (Spotty) PubMed
Expression and Regulation
Operons
Genes
yhaO-sbcE-yhaM
Description
PubMed
Regulation
induced by DNA damage (LexA) PubMed
Regulatory mechanism
LexA: repression, PubMed, in lexA regulon
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yhaO→yhaM

2025-04-04 04:40:40

Bzhu

125

0fb329721ceeda68b6f68eed40be379aa5951941

BCA89E0E7644FD35258E73A933737E90BFD8B07E

Biological materials
Mutant
GP3528 (ΔsbcE::spec), available in Jörg Stülke's lab
MGNA-A663 (yhaN::erm), available at the NBRP B. subtilis, Japan
BKE09920 (sbcE::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_TATAATTCGCAAAGCTGTCA,  downstream forward: _UP4_TAAAAGAGGTTCTATAGCTG
BKK09920 (sbcE::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_TATAATTCGCAAAGCTGTCA,  downstream forward: _UP4_TAAAAGAGGTTCTATAGCTG
References
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Page visits: 5188

Time of last update: 2025-04-04 11:08:26

Author of last update: Jstuelk