spoVAEB

spoVAEB
168

spore germinant protein, essential for the transport of the 1:1 chelate of pyridine-2,6-dicarboxylic acid (DPA(2,6)) and Ca(2+) into spores and DPA release during Germination

Locus
BSU_23402
Molecular weight
12.00 kDa
Isoelectric point
6.25
Protein length
Gene length
Function
spore germination
Product
spore germinant protein
Essential
no
E.C.
null
Synonyms
spoVAEB

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG5839 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
2,440,423  2,440,773
The protein
Catalyzed reaction/ biological activity
forms a membrane channel with SpoVAC PubMed
Structure
spore inner membrane, complex with SpoVAC and SpoVAD PubMed
Additional information
stability in spores depends on SpoVAC PubMed
Expression and Regulation
Operons
Description
Regulation
expressed late during sporulation in the forespore (SigG, SpoVT) PubMed
Regulatory mechanism
SpoVT: activation, PubMed, in spoVT regulon
Sigma factors
SigG: sigma factor, PubMed, in sigG regulon
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spoVAAlysA

2025-03-16 18:09:11

Jstuelk

130

12fce0add6fb0abbed0128cd99d7be2c377e96d5

420F73950DA10EFCB3126E84B350E66BA95D34DD

Biological materials
Mutant
BKE23402 (spoVAEB::erm  trpC2) available at BGSCPubMed, upstream reverse: _UP1_GACAAAAGCCAAAAGGTAGT,  downstream forward: _UP4_TTCAAACCGAAAGGATAATG
BKK23402 (spoVAEB::kan  trpC2) available at BGSCPubMed, upstream reverse: _UP1_GACAAAAGCCAAAAGGTAGT,  downstream forward: _UP4_TTCAAACCGAAAGGATAATG
Labs working on this gene/protein
Peter Setlow, University of Connecticut Health Center, USA
References
Reviews
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Original Publications
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31D6CB7EC20C39C1815CA4552B8B9C4BE304E86B

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Time of last update: 2025-04-06 07:43:17

Author of last update: Jstuelk