fpbP

fpbP
168

petrobactin (3.4-catecholate siderophore) ABC transporter (ATP-binding protein)

Locus
BSU_03820
Molecular weight
28.33 kDa
Isoelectric point
5.09
Protein length
252 aaSequenceBlast
Gene length
759 bpSequenceBlast
Function
acquisition of iron
Product
petrobactin ABC transporter (ATP-binding protein)
Essential
no
Synonyms
fpbP, yclP
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG4604 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
434,256  435,014
The protein
Catalyzed reaction/ biological activity
uptake of the siderophore petrobactin PubMed
Fe(III)-siderophore + ATP + H2O --> Fe(III)-siderophore + ADP + H+ + phosphate (according to UniProt)
Protein family
ABC transporter superfamily (according to UniProt)
Domains
ABC transporter domain (aa 2-236) (according to UniProt)
Structure
4YMS (PDB) (amino acid transporter from Caldanaerobacter subterraneus, 31% identity) PubMed
P94420 (AlphaFold)
Paralogous protein(s)
YusV, FhuC, FecF
Localization
associated to the membrane (via FpbN-FpbO) PubMed
Expression and Regulation
Operons
Genes
fpbN-fpbO-fpbP-fpbQ
Description
PubMed
Regulation
immediately induced upon iron starvation (first wave to allow iron uptake) (Fur) PubMed
Regulatory mechanism
Fur: repression, PubMed, in fur regulon
Open in new tab

fpbN→fpbQ

2025-03-16 15:06:23

Jstuelk

106

74ea5c8bb748d23ec3e0cc6fc1179cb8eab26119

67ED5A2606DC68A56E0956D7F4306EC013902C9F

Biological materials
Mutant
MGNA-C011 (yclP::erm), available at the NBRP B. subtilis, Japan
BKE03820 (fpbP::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_TTGTTTGCTTACATTTCTGA,  downstream forward: _UP4_TAATATATAGAAGAGGTGAG
BKK03820 (fpbP::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_TTGTTTGCTTACATTTCTGA,  downstream forward: _UP4_TAATATATAGAAGAGGTGAG
References
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473628F86C18FE9957841F3C8B45242C90CB341D

Page visits: 5361

Time of last update: 2025-04-05 19:27:26

Author of last update: Jstuelk