ykuQ

ykuQ
168

tetrahydrodipicolinate acetylase

Locus
BSU_14180
Molecular weight
24.84 kDa
Isoelectric point
4.68
Protein length
236 aaSequenceBlast
Gene length
711 bpSequenceBlast
Function
biosynthesis of lysine and peptidoglycan
Product
tetrahydrodipicolinate acetylase
Essential
yes
E.C.
2.3.1.89
Synonyms
ykuQ, dapH
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG2171 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
1,488,973  1,489,683
Phenotypes of a mutant
essential PubMed
The protein
Catalyzed reaction/ biological activity
(S)-2,3,4,5-tetrahydrodipicolinate + acetyl-CoA + H2O --> CoA + L-2-acetamido-6-oxoheptanedioate (according to UniProt)
Protein family
Transferase hexapeptide repeat family (according to UniProt)
Structure
3R8Y (PDB) (from Bacillus anthracis, 80% identity, 96% similarity)
O34981 (AlphaFold)
Expression and Regulation
Operons
Genes
ykuQ-ykuR-ykuS
Description
PubMed
Open in new tab

ykuQ→ykuS

2025-04-04 08:09:44

Jstuelk

94

cd9e2fdc932f01581710e276a91df586a6d39c25

30EDD1FD8E81987B92126BC0CB4F32A7343A78F7

Biological materials
Mutant
MGNA-B340 (ykuQ::erm), available at the NBRP B. subtilis, Japan

716FE06124544C05CC34BA2E643B4DBD27F04998

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Time of last update: 2025-04-07 06:35:28

Author of last update: Jstuelk