yqaH

yqaH
168

antagonist of DnaA, skin element

Locus
BSU_26310
Molecular weight
9.27 kDa
Isoelectric point
5.69
Protein length
85 aaSequenceBlast
Gene length
258 bpSequenceBlast
Function
inhibition of DNA replication, sporulation and biofilm formation
Product
antagonist of DnaA
Essential
no
E.C.
null
Synonyms
yqaH
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms

This gene is a member of the following regulons

Gene
Coordinates
2,697,419 → 2,697,676
Phenotypes of a mutant
overexpression of YqaH causes cell filamentation and abnormal chromosome segregation, suggesting that overproduction of these proteins inhibits DNA replication, perhaps due to the interaction with DnaA  PubMed
The protein
Catalyzed reaction/ biological activity
binds to the DNA-binding domain IV of DnaA to inhibit DNA replication PubMed
Structure
P45905 (AlphaFold)
Localization
Cytoplasm (Homogeneous) PubMed
Expression and Regulation
Operons
Genes
yqaF-yqdA-yqaG-yqaH-yqaI-yqaJ-yqaK-yqaL-yqaM-yqzO-yqaN
Description
PubMed
Regulation
not expressed during normal growth (SknR) PubMed
Regulatory mechanism
SknR: repression, PubMed, in sknR regulon
Sigma factors
SigA: sigma factor, PubMed, in sigA regulon
Additional information
A ncRNA is predicted between yqaJ and yqaI PubMed
Open in new tab

yqaF→yqaN

2025-03-27 20:59:03

Jstuelk

70

e470304f15cd37310c8ed727bb7e0f54ad7c2747

7A6791A58F019385F6E775ED3FB2F9370F7F8AD1

References
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F6AB74740776179E77218DB831FEE03773B7353F

Page visits: 4459

Time of last update: 2025-04-06 21:02:39

Author of last update: Jstuelk