Ffh

• Description: signal recognition particle (SRP) component
  
  

Gene name	ffh
Synonyms
Essential	yes PubMed
Product	signal recognition particle (SRP) component
Function	presecretory protein translocation
Gene expression levels in SubtiExpress: ffh
Interactions involving this protein in SubtInteract: Ffh
Metabolic function and regulation of this protein in SubtiPathways: Ffh
MW, pI	49 kDa, 9.422
Gene length, protein length	1338 bp, 446 aa
Immediate neighbours	ylxM, rpsP
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

protein secretion, essential genes, membrane proteins

The gene

Basic information

• Locus tag: BSU15980

Phenotypes of a mutant

essential PubMed

Database entries

• BsubCyc: BSU15980

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: GTP-binding SRP family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:
  • SecA-Ffh PubMed
  • Ffh-Scr in the signal recognition particle PubMed
  • Ffh-FtsY in the signal recognition particle PubMed

• Localization: cell membrane (according to Swiss-Prot)

Database entries

• BsubCyc: BSU15980

• Structure:
  • 2XXA (complex Ffh-FtsY-Scr RNA, from E. coli) PubMed

• UniProt: P37105

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: ylxM-ffh PubMed

• Expression browser: ffh PubMed

• Sigma factor: SigA PubMed

• Regulation:

• Regulatory mechanism:

• Additional information:
  • number of protein molecules per cell (minimal medium with glucose and ammonium): 353 PubMed
  • number of protein molecules per cell (complex medium with amino acids, without glucose): 751 PubMed

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: