ganR

ganR
168

transcriptional repressor of the galactan utilization operon

Locus
BSU_34170
Molecular weight
37.31 kDa
Isoelectric point
5.4
Protein length
330 aaSequenceBlast
Gene length
993 bpSequenceBlast
Function
regulation of galactan utilization
Product
transcriptional repressor (LacI family)
Essential
no
Synonyms
lacR, yvfJ, ganR
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

List of homologs in different organisms, belongs to COG1609 (Galperin et al., 2021)

This gene is a member of the following regulons

GanR regulon

Gene
Coordinates
3,508,659  3,509,651
The protein
Protein family
LacI family
Domains
HTH lacI-type domain (aa 2-57) (according to UniProt)
Structure
2HSG (PDB) (B. megaterium CcpA, 25% identity) PubMed
O07008 (AlphaFold)
Effectors of protein activity
released from DNA upon binding of galactobiose PubMed
Expression and Regulation
Operons
Genes
ganR
Description
PubMed
Regulation
induced by galactan (binding of galactobiose to GanR) PubMed
Regulatory mechanism
GanR: repression, PubMed, in ganR regulon
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ganR

2025-03-09 18:32:27

Jstuelk

71

f18e3bfeeb8c03bb6051a42cae979fa661fb9f80

AFC0318A8F4F222C9056F7E1BE2132050277CD77

Biological materials
Mutant
GP815 (ganR::spc) available in Jörg Stülke's lab
BKE34170 (ganR::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATTGTATCTGCCTCCATTA,  downstream forward: _UP4_TAAGGATGACTTAGGACACT
BKK34170 (ganR::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATTGTATCTGCCTCCATTA,  downstream forward: _UP4_TAAGGATGACTTAGGACACT
References
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1F787F70C87DEB221709579122D63C2322A84E56

Page visits: 7939

Time of last update: 2025-03-14 08:24:27

Author of last update: Melvin.boenninger