cotZ
168

spore crust anchor protein, necessary for the assembly of the spore crust, the outermost layer of the spore coat

Locus

BSU_11740

Molecular weight

16.00 kDa

Isoelectric point

Protein length

148 aaSequenceBlast

Gene length

447 bpSequenceBlast

Function

spore crust assembly

Product

spore crust anchor protein

Essential

Synonyms

cotZ

Outlinks

BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Hide small RNAsZoom:

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG5888 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene

Coordinates

1,249,442 → 1,249,888

Phenotypes of a mutant

mis-assembly of the spore crust PubMed

The protein

Catalyzed reaction/ biological activity

required for the localization of most crust proteins PubMed

Structure

Q08312 (AlphaFold)

Paralogous protein(s)

CotY

Localization

outermost layer of the spore coat (crust), localization depends on CotE PubMed

more abundant at the mother cell-proximal pole of the forespore PubMed

Expression and Regulation

Operons

Genes

cotY-cotZ

Description

PubMed

Regulation

expressed late during sporulation in the mother cell (SigK) PubMed

Regulatory mechanism

GerR: activation, PubMed, in gerR regulon

GerE: activation, PubMed, in gerE regulon

Sigma factors

SigK: sigma factor, PubMed, in sigK regulon

SigE: sigma factor, PubMed, in sigE regulon

Open in new tab

Biological materials

Mutant

BKE11740 (ΔcotZ::erm trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CATATTATCCCTCCTGCCTT, downstream forward: _UP4_TAATCATAAGCTGGAAAAGC

BKK11740 (ΔcotZ::kan trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CATATTATCCCTCCTGCCTT, downstream forward: _UP4_TAATCATAAGCTGGAAAAGC

References

Reviews

Original Publications

Page visits: 3878

Time of last update: 2025-03-15 11:57:50

Author of last update: Jstuelk

cotZ 168

cotZ
168