rbsR

rbsR
168

transcriptional repressor of the ribose operon

Locus
BSU_35910
Molecular weight
35.70 kDa
Isoelectric point
5.58
Protein length
326 aaSequenceBlast
Gene length
981 bpSequenceBlast
Function
regulation of ribose utilization
Product
transcriptional repressor (LacI family)
Essential
no
Synonyms
rbsR
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG1609 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
3,701,411  3,702,391
The protein
Protein family
LacI family
Domains
HTH lacI-type domain (aa 1-56) (according to UniProt)
Structure
3CTP (PDB) (from Alkaliphilus metalliredigens, 35% identity)
P36944 (AlphaFold)
Expression and Regulation
Operons
Genes
rbsR-rbsK-rbsD-rbsA-rbsC-rbsB
Description
PubMed
Regulation
expressed upon transition into the stationary phase (AbrB) PubMed
Regulatory mechanism
CcpA: repression, PubMed, in ccpA regulon
AbrB: activation, PubMed, in abrB regulon
Sigma factors
SigA: sigma factor, PubMed, in sigA regulon
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rbsR→rbsB

2025-03-10 01:51:35

ghost

89

ecd23e67fb36c12e46381b0bbd805e52a3ac9a7b

9A76230F5BF071D52DFA7084300C0507E658DAA8

Biological materials
Mutant
BKE35910 (rbsR::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CAAAACAGCTCCTCCTTGTT,  downstream forward: _UP4_AAGACGACAAGAAAGGAAGA
BKK35910 (rbsR::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CAAAACAGCTCCTCCTTGTT,  downstream forward: _UP4_AAGACGACAAGAAAGGAAGA
References
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Page visits: 5255

Time of last update: 2025-03-15 11:24:34

Author of last update: Melvin.boenninger