metA

metA
168

homoserine O-succinyltransferase

Locus
BSU_21910
Molecular weight
25.85 kDa
Isoelectric point
6.41
Protein length
301 aaSequenceBlast
Gene length
906 bpSequenceBlast
Function
biosynthesis of methionine
Product
homoserine O-succinyltransferase
Essential
no
E.C.
2.3.1.46
Synonyms
metA, metB
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG1897 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
2,305,378  2,306,283
The protein
Catalyzed reaction/ biological activity
acetyl-CoA + L-homoserine --> CoA + O-acetyl-L-homoserine (according to UniProt)
Protein family
MetA family (single member, according to UniProt)
Structure
2GHR (PDB) (from Bacillus cereus, 60% identity, 77% similarity) PubMed
P54167 (AlphaFold)
Expression and Regulation
Operons
Genes
metA-ugtP
Description
PubMed
Sigma factors
SigM: sigma factor, PubMed, in sigM regulon
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metA→ugtP

2025-04-07 09:41:50

ghost

140

45e856ff37b7ee445afb9c87f96abb81194264ae

4B45D0C21B6BA8DCA11EA8FC7ACD2A28343A2152

Biological materials
Mutant
BKE21910 (metA::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CAACGTGCCACCTCCATTAT,  downstream forward: _UP4_TAATTTTTCTTTTTTTAGTG
BKK21910 (metA::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CAACGTGCCACCTCCATTAT,  downstream forward: _UP4_TAATTTTTCTTTTTTTAGTG
References
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1217330ECD588E24E42FF9FED2A097CEF32785F3

Page visits: 3567

Time of last update: 2025-04-13 16:56:50

Author of last update: Melvin.boenninger