araR

araR
168

transcriptional repressor (GntR family, LacI family) of the arabinose utilization genes

Locus
BSU_33970
Molecular weight
43.00 kDa
Isoelectric point
6.34
Protein length
384 aaSequenceBlast
Gene length
1155 bpSequenceBlast
Function
regulation of arabinose utilization
Product
transcriptional repressor (GntR family, LacI family)
Essential
no
Synonyms
araR, araC, yvbS
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG1609 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
3,485,604  3,486,758
Phenotypes of a mutant
inactivation of ''araR'' reduces sporulation efficiency to 28% that of wild type cells PubMed
The protein
Protein family
GntR family: N-terminal DNA-binding domain, LacI family: C-terminal effector-binding domain
Domains
N-terminal DNA-binding domain (GntR family)
C-terminal effector-binding domain (LacI family)
HTH gntR-type domain (aa 1-70) (according to UniProt)
Structure
3TB6 (PDB) (effector-binding domain) PubMed
P96711 (AlphaFold)
Localization
cytoplasm (according to Swiss-Prot)
Expression and Regulation
Operons
Genes
araR
Description
PubMed
Regulation
induced by arabinose (AraR) PubMed
Regulatory mechanism
AraR: repression, PubMed, in araR regulon
Sigma factors
SigA: sigma factor, PubMed, in sigA regulon
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araR

2025-03-10 23:58:59

ghost

83

d2286298f3ef689746c3c4c984f3c45640b8c9d3

5D0C5E53C9A992BBDE4EE32495B12C8CA2AFA294

Biological materials
Mutant
BKE33970 (araR::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATATCCATTCCTCCAAAAT,  downstream forward: _UP4_TAAAAAAAGCAATGTATGGG
BKK33970 (araR::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATATCCATTCCTCCAAAAT,  downstream forward: _UP4_TAAAAAAAGCAATGTATGGG
References
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Page visits: 6902

Time of last update: 2025-03-15 09:56:34

Author of last update: Jstuelk