rplE

rplE
168

ribosomal protein uL5

Locus
BSU_01280
Molecular weight
20.00 kDa
Isoelectric point
9.96
Protein length
179 aaSequenceBlast
Gene length
540 bpSequenceBlast
Function
translation
Product
ribosomal protein L5 (uL5)
Essential
yes
Synonyms
rplE
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG0094 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
141,195 → 141,734
Phenotypes of a mutant
essential PubMed
The protein
Protein family
universal ribosomal protein uL5 family (single member, according to UniProt)
Structure
1IQ4 (PDB) (Geobacillus stearothermophilus)
3J9W (PDB) (the ribosome) PubMed
P12877 (AlphaFold)
Expression and Regulation
Operons
Genes
rpsJ-rplC-rplD-rplW-rplB-rpsS-rplV-rpsC-rplP-rpmC-rpsQ-rplN-rplX-rplE-rpsN-rpsH-rplF-rplR-rpsE-rpmD-rplO-secY-adk-map-oapB-infA-rpmJ-rpsM-rpsK-S56-rpoA-rplQ
Description
PubMed
Regulation
strongly repressed in response to glucose starvation in M9 medium PubMed
likely autorepression of operon expression upon binding of excess of one ribosomal protein to the untranslated region of the mRNA PubMed
expression is reduced in motile cells as compared to non-motile cells PubMed
Regulatory mechanism
stringent response: negative regulation, in stringent response
Sigma factors
SigA: sigma factor, PubMed (two promoters, about 140bp and 200bp upstream of the start codon), in sigA regulon
Additional information
term-seq has identified a potential novel regulatory RNA element (protein-dependent leader) including an intrinsic transcription terminator upstream of rpsJ PubMed
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rpsJ→rplQ

2025-03-16 17:24:44

Jstuelk

145

911D53E804EEFE6335D6A0F79722F9870F387CD3

9027854E648E8BF3E4A3C8492D350C69AC71C218

References
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F34C72BF4C3A8FF710D3B65F87324400ECDE3610

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Time of last update: 2025-03-22 10:55:16

Author of last update: Jstuelk