araD

araD
168

L-ribulose-phosphate 4-epimerase

Locus
BSU_28780
Molecular weight
25.54 kDa
Isoelectric point
5.24
Protein length
229 aaSequenceBlast
Gene length
690 bpSequenceBlast
Function
arabinose utilization
Product
L-ribulose-phosphate 4-epimerase
Essential
no
E.C.
5.1.3.4
Synonyms
araD
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG0235 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
2,944,983  2,945,672
The protein
Catalyzed reaction/ biological activity
L-ribulose 5-phosphate --> D-xylulose 5-phosphate (according to UniProt)
Protein family
aldolase class II family (with MtnB, according to UniProt)
Structure
1K0W (PDB) (from   \t   Escherichia coli, 59% identity, 74% similarity)\tPubMed
P94525 (AlphaFold)
Expression and Regulation
Operons
Genes
araA-araB-araD-araL-araM-araN-araP-araQ-abfA
Description
PubMed
Regulation
induced by arabinose (AraR) PubMed
Regulatory mechanism
CcpA: repression, PubMed, in ccpA regulon
AraR: repression, PubMed, in araR regulon
Sigma factors
SigA: sigma factor, PubMed, in sigA regulon
Additional information
the mRNA is very stable (half-life > 15 min) PubMed
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araA→abfA

2025-03-17 19:30:39

ghost

142

b7d3312ef868c449eb18db3a2b2bf36130567026

7BE2C086CD88758AEADFA2166B6FC6182EB55613

Biological materials
Mutant
BKE28780 (araD::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_TTCAAGCATGCTCCATCACC,  downstream forward: _UP4_CATTTTTATCGAAAACACGG
BKK28780 (araD::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_TTCAAGCATGCTCCATCACC,  downstream forward: _UP4_CATTTTTATCGAAAACACGG
References
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3859854178E573AE8ACCE6DF85E32C495D316DA1

Page visits: 4341

Time of last update: 2025-03-18 04:10:14

Author of last update: Melvin.boenninger