patB

patB
168

cystathione-beta-lyase

Locus
BSU_31440
Molecular weight
42.63 kDa
Isoelectric point
5.44
Protein length
387 aaSequenceBlast
Gene length
1164 bpSequenceBlast
Function
biosynthesis of methionine
Product
cystathione-beta-lyase
Essential
no
E.C.
4.4.1.8
Synonyms
patB
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG1168 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
3,228,778  3,229,941
The protein
Catalyzed reaction/ biological activity
H2O + L,L-cystathionine --> L-homocysteine + NH4+ + pyruvate (according to UniProt)
Protein family
class-II pyridoxal-phosphate-dependent aminotransferase family (according to UniProt)
Cofactors
PLP (according to UniProt)
Structure
3T32 (PDB) (from B. anthracis, 46% identity, 75% similarity)
Q08432 (AlphaFold)
Expression and Regulation
Operons
Genes
patB
Description
PubMed
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patB

2025-03-17 16:28:46

ghost

83

e8c1b578f615f86fc57ea79c5c922556907e4fa9

F6A640B080BD7F951D257D4B22A2E0C06EE55AFA

Biological materials
Mutant
1A952 ( patB::cat), PubMed, available at BGSC
BKE31440 (patB::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATTCTGTTACCCCCTCATG,  downstream forward: _UP4_TAAATATAGCTGTAAACGCC
BKK31440 (patB::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATTCTGTTACCCCCTCATG,  downstream forward: _UP4_TAAATATAGCTGTAAACGCC
References
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11B54D438CDD2EAA4A87A6B99851A3B123EA4A1F

Page visits: 2398

Time of last update: 2025-03-17 17:04:41

Author of last update: Melvin.boenninger