znuC
168

high-affinity ABC transporter for zinc (ATP-binding protein)

Locus

BSU_02860

Molecular weight

26.17 kDa

Isoelectric point

8.2

Protein length

231 aaSequenceBlast

Gene length

696 bpSequenceBlast

Function

zinc uptake

Product

ABC transporter for zinc (ATP-binding protein)

Essential

E.C.

3.6.3.-

Synonyms

znuC, ycdI, adcC

Outlinks

BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Hide small RNAsZoom:

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG1121 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene

Coordinates

309,347 310,042

Phenotypes of a mutant

reduced genetic competence, can be rescued by the addition of excess zinc PubMed

reduced expression of the ''comFA-comFB-comFC-yvyF-flgM-flgN-flgK-flgL'' operon PubMed

The protein

Protein family

ABC transporter superfamily (according to UniProt)

Domains

ABC transporter domain (aa 4-230) (according to UniProt)

Structure

4YMS (PDB) (from Caldanaerobacter subterraneus, 31% identity) PubMed

O34946 (AlphaFold)

Localization

cell membrane (according to UniProt)

Expression and Regulation

Operons

Genes

znuA-znuC-znuB

Description

PubMed

Regulation

induced by zinc starvation (Zur) PubMed

Regulatory mechanism

Zur: repression, in the presence of zinc PubMed, in zur regulon

Sigma factors

SigA: sigma factor, PubMed, in sigA regulon

Open in new tab

Biological materials

Mutant

MGNA-B981 (ycdI::erm), available at the NBRP B. subtilis, Japan

BKE02860 (znuC::erm trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CATGTTAATCTTCCTTTCTC, downstream forward: _UP4_GGATGGAAATGTTTGACTTG

BKK02860 (znuC::kan trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CATGTTAATCTTCCTTTCTC, downstream forward: _UP4_GGATGGAAATGTTTGACTTG

References

Page visits: 4843

Time of last update: 2025-03-21 07:59:04

Author of last update: Jstuelk

znuC 168

znuC
168