motA

motA
168

H+-coupled MotA-MotB flagellar stator

Locus
BSU_13690
Molecular weight
29.19 kDa
Isoelectric point
5.01
Protein length
270 aaSequenceBlast
Gene length
813 bpSequenceBlast
Function
Motility and chemotaxis
Product
flagellar stator subunit
Essential
no
Synonyms
motA
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG1291 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
1,434,433  1,435,245
Phenotypes of a mutant
loss of swimming and Swarming motility PubMed
mucoid phenotype due to the DegU-P activated overexpression of the ''capB-capC-capA-capE'' operon and resulting overproduction of poly-gamma-glutamate PubMed
not essential for pellicle biofilm formation, but mutant is outcompeted by the wild-type strain when competed during pellicle formation PubMed
The protein
Protein family
motA family (with MotP, according to UniProt)
Structure
6YSF (the MotA5-MotB2 complex from Clostridium sporogenes) PubMed
P28611 (AlphaFold)
Effectors of protein activity
the interaction with MotI inhibits MotA activity PubMed
Paralogous protein(s)
MotP
Localization
anchored to the cell wall, extending through the cell membrane PubMed
Expression and Regulation
Operons
Genes
motA-motB
Description
PubMed
Sigma factors
SigD: sigma factor, PubMed, in sigD regulon
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motA→motB

2025-03-11 07:44:01

ghost

128

f511063e389d3698178011e8d1f147d1a31d3316

AF120FAC2CA2C8D759F36B320DEAC937613576A3

Biological materials
Mutant
1A631 ( motA::erm), PubMed, available at BGSC
1A923 ( motA::erm), PubMed, available at BGSC
DS7498 (marker-less  in NCIB3610) PubMed
BKE13690 (motA::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATAGTTTTCACCAAATCCT,  downstream forward: _UP4_TTTGCAGAACAAGGAGAGGC
BKK13690 (motA::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATAGTTTTCACCAAATCCT,  downstream forward: _UP4_TTTGCAGAACAAGGAGAGGC
References
Reviews
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Original Publications
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86C729C7D5ABEE519ADC4A893940600BBB655EF1

Page visits: 5082

Time of last update: 2025-03-16 22:50:58

Author of last update: Jstuelk