araM

araM
168

glycerol-1-phosphate dehydrogenase, L-arabinose operon

Locus
BSU_28760
Molecular weight
42.90 kDa
Isoelectric point
5.63
Protein length
394 aaSequenceBlast
Gene length
1185 bpSequenceBlast
Function
biosynthesis of phosphoglycerolipids
Product
glycerol-1-phosphate dehydrogenase
Essential
no
E.C.
1.1.1.261
Synonyms
araM, yseB
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG0371 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
2,943,006  2,944,190
The protein
Catalyzed reaction/ biological activity
NAD+ + sn-glycerol 1-phosphate --> dihydroxyacetone phosphate + H+ + NADH (according to UniProt)
NADP+ + sn-glycerol 1-phosphate --> dihydroxyacetone phosphate + H+ + NADPH (according to UniProt)
Protein family
glycerol-1-phosphate dehydrogenase family (single member, according to UniProt)
Cofactors
NADH (according to UniProt)
Structure
P94527 (AlphaFold)
Localization
cytoplasm (according to UniProt)
Expression and Regulation
Operons
Genes
araA-araB-araD-araL-araM-araN-araP-araQ-abfA
Description
PubMed
Regulation
induced by arabinose (AraR) PubMed
Regulatory mechanism
CcpA: repression, PubMed, in ccpA regulon
AraR: repression, PubMed, in araR regulon
Sigma factors
SigA: sigma factor, PubMed, in sigA regulon
Additional information
the mRNA is very stable (half-life > 15 min) PubMed
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araA→abfA

2025-03-08 15:01:32

ghost

141

b7d3312ef868c449eb18db3a2b2bf36130567026

7BE2C086CD88758AEADFA2166B6FC6182EB55613

Biological materials
Mutant
MGNA-A985 (araM::erm), available at the NBRP B. subtilis, Japan
BKE28760 (araM::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CTGAACGTCAGCTGCGATAC,  downstream forward: _UP4_TAGCCCGCACCTCGAATGGA
BKK28760 (araM::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CTGAACGTCAGCTGCGATAC,  downstream forward: _UP4_TAGCCCGCACCTCGAATGGA
References
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16EE17461B4AB467A4F8172FD3E335073AD2B1D8

Page visits: 4412

Time of last update: 2025-03-13 21:20:18

Author of last update: Melvin.boenninger