oppB

oppB
168

oligopeptide ABC transporter (permease)

Locus
BSU_11440
Molecular weight
33.92 kDa
Isoelectric point
9.86
Protein length
311 aaSequenceBlast
Gene length
936 bpSequenceBlast
Function
initiation of sporulation, competence development
Product
oligopeptide ABC transporter (permease)
Essential
no
Synonyms
oppB, spo0KB
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG0601 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
1,221,594 → 1,222,529
Phenotypes of a mutant
reduced survival after DNA replication arrest imposed by inhibition of PolC activity PubMed
The protein
Catalyzed reaction/ biological activity
required for the uptake of quorum sensing peptides such as PhrH PubMed
Protein family
Binding-protein-dependent transport system permease family (according to UniProt)
OppBC subfamily (according to UniProt)
Domains
ABC transmembrane type-1 domain (aa 94-295) (according to UniProt)
Structure
P24138 (AlphaFold)
Paralogous protein(s)
AppB, DppB
Localization
cell membrane PubMed
Expression and Regulation
Operons
Genes
oppA-oppB-oppC-oppD-oppF
Description
PubMed
Regulation
expressed in the absence of good nitrogen sources (glutamine or ammonium) (TnrA) PubMed
Regulatory mechanism
TnrA: activation, PubMed, in tnrA regulon
CodY: repression, no derepression occurs, however, in a CodY mutant, due to increased repression by ScoC PubMed, in codY regulon
ScoC: repression, PubMed, in scoC regulon
Additional information
A ncRNA is predicted between 'trpS' and 'oppA' PubMed
Open in new tab

oppA→oppF

2025-03-15 18:44:06

ghost

133

70070544ac18e9c940a824c6284e4ee6740ee2e5

E173E2B9FD2733A51C073CE2F9C6DE998F2580A2

Biological materials
Mutant
GP2063 (''oppB::spc''), available in Jörg Stülke's lab
GP2097 (D(''oppA-oppB-oppC-oppD-oppF)::aphA3''), available in Jörg Stülke's lab
BKE11440 (ΔoppB::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CAAGGGGGAACACCTCCATG,  downstream forward: _UP4_AAAGCAAAGAAAGGAGCCTA
BKK11440 (ΔoppB::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CAAGGGGGAACACCTCCATG,  downstream forward: _UP4_AAAGCAAAGAAAGGAGCCTA
References
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Time of last update: 2025-03-16 11:40:31

Author of last update: Jstuelk