sigW
168
RNA polymerase ECF-type sigma factor SigW, required for the adaptation to membrane active agents, activated by alkaline shock and by polymyxin B, vancomycin, cephalosporin C, D-cycloserine, and triton X-100
Locus
BSU_01730
Molecular weight
21.57 kDa
Isoelectric point
8.61
Function
adaptation to membrane-active compounds
Product
RNA polymerase ECF-type sigma factor SigW
Essential
no
Synonyms
sigW, ybbL
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG1595 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
194,849 195,412
Phenotypes of a mutant
The protein
Protein family
Sigma-70 factor family (according to UniProt)
ECF subfamily (according to UniProt)
Structure
Effectors of protein activity
RsiW acts as antagonist of SigW (anti-SigW)
Expression and Regulation
Operons
Description
Regulation
Regulatory mechanism
Sigma factors
Additional information
the mRNA is very stable (half-life > 15 min) PubMed
Biological materials
Mutant
Labs working on this gene/protein
John Helmann, Cornell University, USA Homepage
Thomas Wiegert, University of Bayreuth, Germany Wiegert-Dateien/Thomas Wiegert.html Homepage
References
Page visits: 9467
Time of last update: 2025-03-17 02:25:10
Author of last update: Jstuelk