tcyB

tcyB
168

cystine and diaminopimelate ABC transporter (permease)

Locus
BSU_03600
Molecular weight
26.24 kDa
Isoelectric point
9.93
Protein length
234 aaSequenceBlast
Gene length
705 bpSequenceBlast
Function
cystine and diaminopimelate uptake
Product
cystine and diaminopimelate ABC transporter (permease), membrane protein
Essential
no
Synonyms
tcyB, yckJ
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG0765 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
409,965  410,669
The protein
Catalyzed reaction/ biological activity
uptake of cystine and diaminopimelate PubMed
Protein family
Binding-protein-dependent transport system permease family (according to UniProt)
Structure
4YMS (PDB) (amino acid transporter from Caldanaerobacter subterraneus, 37% identity) PubMed
P42200 (AlphaFold)
Paralogous protein(s)
YxeN, YckA
Localization
membrane protein PubMed
Expression and Regulation
Operons
Genes
tcyA-tcyB-tcyC
Description
PubMed
Regulation
strongly repressed in response to glucose starvation in M9 medium PubMed
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tcyA→tcyC

2025-03-16 16:05:08

Jstuelk

121

4d611b63f86c92d9ecb8c2daaa53e692acd195f5

768128284DD011A0C571EBC11696DA21513C3B17

Biological materials
Mutant
MGNA-C059 (yckJ::erm), available at the NBRP B. subtilis, Japan
BKE03600 (tcyB::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CGTGCCAAGCGTCAATGCCG,  downstream forward: _UP4_GTGGCCAAATAAGGAGGTTC
BKK03600 (tcyB::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CGTGCCAAGCGTCAATGCCG,  downstream forward: _UP4_GTGGCCAAATAAGGAGGTTC
References
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9400DF25487461E3738DDDC72BDDB1589281409D

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Time of last update: 2025-03-20 18:02:30

Author of last update: Jstuelk