Difference between revisions of "PrpC"
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=== Database entries === | === Database entries === | ||
| − | * '''Structure:''' | + | * '''Structure:''' [http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1TXO 1TXO] (from ''Mycobacterium tuberculosis'', 34% identity, 54% similarity) {{PubMed|15530359}} |
* '''UniProt:''' [http://www.uniprot.org/uniprot/O34779 O34779] | * '''UniProt:''' [http://www.uniprot.org/uniprot/O34779 O34779] | ||
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=References= | =References= | ||
| − | <pubmed>19246764,10986276,,16025310, 10986276, 12399479, 18757537, 19246764 </pubmed> | + | <pubmed>19246764,10986276,17693724 ,16025310, 10986276, 12399479, 18757537, 19246764 15530359 </pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 09:52, 18 February 2010
- Description: protein phosphatase
| Gene name | prpC |
| Synonyms | yloO |
| Essential | no |
| Product | protein phosphatase |
| Function | antagonist of PrkC-dependent phosphorylation |
| Metabolic function and regulation of this protein in SubtiPathways: Central C-metabolism | |
| MW, pI | 27 kDa, 4.355 |
| Gene length, protein length | 762 bp, 254 aa |
| Immediate neighbours | yloN, prkC |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Locus tag: BSU15760
Phenotypes of a mutant
A prpC mutant is less lytic in late stationary phase. PubMed
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: A phosphoprotein + H2O = a protein + phosphate (according to Swiss-Prot)
- Protein family:
- Paralogous protein(s):
Proteins dephosphorylated by PrpC
CpgA, EF-Tu, YezB PubMed, HPr PubMed
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s): divalent cations such as magnesium or manganese
- Effectors of protein activity: inhibited by inorganic phosphate and glycero-2-phosphate PubMed
- Interactions:
- Localization:
Database entries
- UniProt: O34779
- KEGG entry: [2]
- E.C. number: 3.1.3.16
Additional information
Expression and regulation
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant: OMG401 (aphA3), available in the Stülke lab
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
