AscR

• Description: transcriptional activator of the ytmI-tcyJ-tcyK-tcyL-tcyM-tcyN-ytmO-ytnI-ytnJ-ribR-ytnL-ytnM operon
  
  

Gene name	ytlI
Synonyms
Essential	no
Product	transcriptional activator (LysR family)
Function	regulation of sulphur metabolism
Gene expression levels in SubtiExpress: ytlI
Metabolic function and regulation of this protein in SubtiPathways: Riboflavin / FAD
MW, pI	35 kDa, 6.228
Gene length, protein length	924 bp, 308 aa
Immediate neighbours	ytmI, ytkL
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

biosynthesis/ acquisition of amino acids, transcription factors and their control

This gene is a member of the following regulons

CymR regulon

The YtlI regulon:

• ytmI-tcyJ-tcyK-tcyL-tcyM-tcyN-ytmO-ytnI-ytnJ-ribR-ytnL-ytnM

The gene

Basic information

• Locus tag: BSU29400

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: LysR family

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure:

• UniProt: O35038

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: ytlI PubMed

• Expression browser: ytlI PubMed

• Sigma factor: SigA PubMed

• Regulation:
  • repressed in the presence of cysteine (CymR) PubMed

• Regulatory mechanism:
  • CymR: transcription repression PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: