cotR

cotR
168

outer spore coat protein, lipolytic enzyme

Locus
BSU_34530
Molecular weight
35.20 kDa
Isoelectric point
10.2
Protein length
320 aaSequenceBlast
Gene length
963 bpSequenceBlast
Function
hydrolysis of lysophospholipids
Product
outer spore coat lipolytic enzyme
Essential
no
Synonyms
cotR, yvdO
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG3621 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
3,544,642  3,545,604
The protein
Catalyzed reaction/ biological activity
release of myristic acid from 1-myristoly-2-lyso-sn-glycero-3-phosphocholine PubMed
Domains
PNPLA domain (aa 7-182) (according to UniProt)
Structure
O06996 (AlphaFold)
Localization
outer spore coat PubMed
Expression and Regulation
Operons
Genes
cotR
Description
PubMed
Regulation
expressed late during sporulation in the mother cell (SigK) PubMed
Sigma factors
SigK: sigma factor, PubMed, in sigK regulon
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cotR

2025-03-10 20:59:50

ghost

50

0ffdc7d2a8f6b05c7bc92631a00e2f7dd56d1b3c

E323B0E02D3DBC8A6A3EB503D9210018683D918C

Biological materials
Mutant
MGNA-B621 (yvdO::erm), available at the NBRP B. subtilis, Japan
BKE34530 (cotR::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CAAAGCTGATGTCTCCTTTC,  downstream forward: _UP4_TAATTATTTATTTTAAATCA
BKK34530 (cotR::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CAAAGCTGATGTCTCCTTTC,  downstream forward: _UP4_TAATTATTTATTTTAAATCA
References
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6B9B62D9687331CDC2677C78A624FA609C8F8CFC

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Time of last update: 2025-04-13 15:03:08

Author of last update: Jstuelk